It is not unusual for musical comedy characters to undergo transformations. The genre is filled with lonely women who find love, vindictive men who turn generous, and insecure bumblers who gain confidence. All of the above are on display in the York Theatre Company’s breezy premiere of The Jerusalem Syndrome, but the writing team of Laurence Holzman and Felicia Needleman serve up this evolution with a new twist. Well, an ancient twist, actually. By play’s end, its five leads are all better people. But they achieve this feat by spending most of the show thoroughly convinced that they are characters from the Bible.